Anna Hutchinson’s Webpage
I am a PhD student at the MRC Biostatistics Unit at the University of Cambridge (iCase studentship in collaboration with GlaxoSmithKline). My supervisors are Dr Chris Wallace and Dr David Wille and I am a member of the Wallace group and the Statistical Omics (SOMX) group.
Prior to starting my PhD, I completed a degree in Mathematics and Biology at Durham University (1st Class Honours). During my degree, I spent a year at the University of Calgary completing a variety of human genetics and statistics courses. During this time, I worked as a research assistant with Dr Ying Yan on the analysis of objectifying randomised clinical trials. I also interned at the Centre for Computational Biology at the University of Birmingham, working with Professor Jean-Baptiste Cazier to compare ovarian-breast cancer causing mutations between white British and Punjabi women. I am conscious of the Eurocentric biases of genetic studies and hope that more effort is placed on the under-represented non-European populations in the coming years.
Coming from a Natural Sciences background, I am interested in using Bayesian techniques to answer biological questions. My research involves determining the true coverage of credible sets in Bayesian fine-mapping genetic association studies. I also have interests in incorporating functional genomics data (such as genome segmentation data, Hi-C data and CRISPR data) with GWAS and fine-mapping results to improve our understanding of the biology of disease.
My current research involves investigating the true coverage of credible sets from Bayesian fine-mapping of genetic causal variants and deriving a “corrected coverage” estimate.
See the R package webpage here: https://annahutch.github.io/corrcoverage/
Weekly summaries of my PhD work are posted here: https://annahutch.github.io/PhD/
Conferences + Talks
- SEGEG @ The Big Data Institute, Oxford – 6 November 2019
- Quantitative Genomics (QG19) ** BEST LONG TALK AWARD ** – 10 June 2019
- GSK Human Genetics Group Meeting – 6 June 2019
- Mathematical and Statistical Aspects of Molecular Biology (MASAMB) ** BEST STUDENT TALK AWARD ** – 26 April 2019
- Building Bridges in Medical Science (BBMS) (Poster)- 8 March 2019
- St Catharine’s College Graduate Symposium (Organiser) – 27 February 2019
I enjoy walking, travelling, board games (I am a ‘Settlers of Catan’ and ‘Splendor’ expert!) and meeting new people. I am a member of St Catharine’s College, where I enjoy my role as the MCR social secretary. I am also the PhD Student Rep at the MRC Biostatistics Unit.